Dr. Bunz is a research scientist in the Molecular Radiation Sciences division of the Radiation Oncology department. Prior to his appointment to the faculty in 2001, Dr. Bunz completed a research fellowship at the Howard Hughes Medical Research Institute at the Johns Hopkins University School of Medicine. He serves as Director of the Cell Imaging core facility of the Sidney Kimmel Comprehensive Cancer Center, and is a member of the Cellular and Molecular Medicine (CMM) graduate program and the Institute for NanoBioTechnology.

The Bunz laboratory is dedicated to studying the chromosome-damaging effects of ionizing radiation, ultraviolet radiation, and chemotherapeutic drugs on human cells. The cellular responses to DNA damage are coordinated by a complex and interconnected network of signaling proteins. Recently developed tools allow the genetic basis of DNA damage signaling to be systematically studied in cell culture. Current studies in the Bunz laboratory focus on how individual components of the DNA damage signaling network affect cell cycle regulation and cell proliferation, genetic stability, cell survival and the suppression of tumorigenesis.